381 research outputs found

    Bridging the Gap Between the Least and the Most Influential Twitter Users

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    Social networks play an increasingly important role in shaping the behaviour of users of the Web. Conceivably Twitter stands out from the others, not only for the platform's simplicity but also for the great influence that the messages sent over the network can have. The impact of such messages determines the influence of a Twitter user and is what tools such as Klout, PeerIndex or TwitterGrader aim to calculate. Reducing all the factors that make a person influential into a single number is not an easy task, and the effort involved could become useless if the Twitter users do not know how to improve it. In this paper we identify what specific actions should be carried out for a Twitterer to increase their influence in each of above-mentioned tools applying, for this purpose, data mining techniques based on classification and regression algorithms to the information collected from a set of Twitter users.This work has been partially founded by the European Commission Project ”SiSOB: An Observatorium for Science in Society based in Social Models” (http://sisob.lcc.uma.es) (Contract no.: FP7 266588), ”Sistemas Inalámbricos de Gestión de Información Crítica” (with code number TIN2011-23795 and granted by the MEC, Spain) and ”3DTUTOR: Sistema Interoperable de Asistencia y Tutoría Virtual e Inteligente 3D” (with code number IPT-2011-0889- 900000 and granted by the MINECO, Spain

    DASSCi: Avatares Digitales Deportivos en Ciudades Inteligentes.

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    Las nuevas tecnologías han impulsado la evolución de las ciudades inteligentes, las cuales buscan mejorar la calidad de vida de sus habitantes y optimizar la gestión de recursos urbanos a través de soluciones innovadoras y sostenibles. En este trabajo, se aborda el diseño e implementación de una aplicación móvil para el fomento de la actividad deportiva en la ciudad de Málaga, basada en el concepto de Digital Avatars. Dicho término se basa en el modelo People as a Service, y hace referencia a entidades digitales que residen en los smartphones de los usuarios y permiten controlar la información personal compartida, proporcionando una gestión segura y colaborativa de los datos. La aplicación desarrollada en este trabajo promueve la actividad física y la interacción social entre los ciudadanos, permitiéndoles registrar sus entrenamientos, conocer todas las instalaciones deportivas disponibles en la ciudad, socializar a través de la realización de entrenamientos en grupo y competir entre ellos para conocer quién es más activo deportivamente.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

    Estudio para la implementación del manual de control interno caso (Gobierno Municipal del Cantón Puerto Quito, Provincia de Pichincha)

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    El presente trabajo se basa en el estudio para la implementación de un manual de control interno para la sección de contabilidad del Gobierno cantonal de Puerto Quito, Cantón Puerto Quito, Provincia de Pichincha, en el periodo de enero a junio del 2018”. Y que plantea como problema, ¿Cuál será la incidencia del estudio para  la implementación de un manual de control interno para sección de contabilidad para disminuir riesgos en la ejecución de actividades encaminadas al cumplimiento de los objetivos y en que los ingresos y gastos aplicables a las operaciones del municipio, sean registradas e informadas adecuadamente, con el propósito de preparar estados e informes financieros confiables? cuyo objetivo general es dotar a la administración de un instrumento que describa y unifique los procedimientos y criterios mínimos que faciliten la evaluación del sistema de control interno por parte de las unidades de control interno, con el fin de fomentar su fortalecimiento, proporcionando información retro alimentadora para toma de decisiones en proceso de gestión de la municipalidad, contribuyendo así, a mejorar la eficiencia y efectividad, lo que redundara en beneficios de los intereses del Gobierno Cantonal de Puerto Quito y de las Sección de Contabilidad

    Estrategias para mitigar el riesgo de lavado de activos en sectores empresariales del Ecuador

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    Son muchos los mecanismos para lavar activos, no solamente en nuestro país, sino a nivel mundial. Estudios realizados indican que el lavado de activos alcanza aproximadamente USD 320 000 millones en el mundo, de los cuales USD 150 000 millones estarían en América Latina. Esta investigación se basa en  plantear estrategias para reducir el riesgo de lavado de activos en los sectores económicos vulnerables del Ecuador mediante la implementación de procedimientos de debida diligencia, puesto que el crimen organizado es muy ingenioso al determinar nuevas formas para delinquir, esto hace que diversos sectores económicos sean vulnerables y que surja la necesidad de contar con la habilidad suficiente para detectar, prevenir y mejorar su sistema operativo y sus prácticas empresariales. La globalización, la economía a nivel mundial, la facilidad en las comunicaciones y movilización, las relaciones y la creciente interdependencia económica entre países, ha atraído como consecuencia mayores oportunidades para lavar dinero y tratar de legitimar toda clase de fondos ilegales. Las empresas que son utilizadas para ejecutar este crimen, sufren desenlaces muy fuertes, así como también sus accionistas, directivos y empleados y en el peor de los casos puede causar su cierre y consecuentemente la desaparición del negocio

    Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

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    BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

    Estudio de ecosistemas terrestres y acuáticos ubicados en el parque nacional natural cueva de los guácharos (acevedo, huila)

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    Los estudios realizados durante el tiempo en el que se realizó la salida de campo de la asignatura Ecología Regional Continental del 3 al 17 de septiembre de 2010 permitieron determinar ciertas características y estados de calidad en los sistemas acuáticos y vegetales (bosque subandino) del Parque Nacional Natural Cueva de los Güácharos(PNNCG). Para el estudio limnológico se realizaron muestreos en varios ecosistemas acuáticos: Laguna Encantada, Quebrada Chánchiras, Quebrada La Lindosa, Cascada Cristales, Rí­o Suaza, Cueva de los Guacharos y Cueva del Indio. Se tomaron muestras a de variales fisicoquímicas y de comunidades biológicas (perifiton, plancton, macroinvertebrados). Las aguas de la región son de temperaturas medias y se mineralizan al pasar por el sistema de cuevas; son ligeramente alcalinas y bajas en nutrientes (oligotróficas) y transportan bajas a moderadas cantidades de sólidos suspendidos. Los datos fisicoquímicos que caracterizan a los ecosistemas acuáticos del PNNCG corresponden a sistemas típicos neotropicales, con baja intervención humana y condiciones propias de ambientes cársticos. La materia orgánica aportada por la vegetación riparia y por las macrófitas sustenta diferentes órdenes de macroinvertebrados, siendo los más representativos Diptera, Ephemeroptera, Hemíptera y Trichoptera. El bosque subandino estudiado se encuentra en proceso de desarrollo debido a que presenta una mayor cantidad de arboles del conjunto del futuro; no obstante, el conjunto del presente, aunque en una menor proporción, se encuentra bien establecido. Esto también se puede observar en los mapas de cobertura vegetal del estrato arbóreo, donde el dosel es continuo y solamente se interrumpe por los disturbios ocasionados por la muerte y caída de árboles del conjunto del presente, lo que genera claros en el bosque y permite que los arboles del conjunto del futuro desarrollen su cobertura

    Identification of regulatory variants associated with genetic susceptibility to meningococcal disease.

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    Non-coding genetic variants play an important role in driving susceptibility to complex diseases but their characterization remains challenging. Here, we employed a novel approach to interrogate the genetic risk of such polymorphisms in a more systematic way by targeting specific regulatory regions relevant for the phenotype studied. We applied this method to meningococcal disease susceptibility, using the DNA binding pattern of RELA - a NF-kB subunit, master regulator of the response to infection - under bacterial stimuli in nasopharyngeal epithelial cells. We designed a custom panel to cover these RELA binding sites and used it for targeted sequencing in cases and controls. Variant calling and association analysis were performed followed by validation of candidate polymorphisms by genotyping in three independent cohorts. We identified two new polymorphisms, rs4823231 and rs11913168, showing signs of association with meningococcal disease susceptibility. In addition, using our genomic data as well as publicly available resources, we found evidences for these SNPs to have potential regulatory effects on ATXN10 and LIF genes respectively. The variants and related candidate genes are relevant for infectious diseases and may have important contribution for meningococcal disease pathology. Finally, we described a novel genetic association approach that could be applied to other phenotypes

    Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

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    Background: Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods: This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the GlobalSurg 1 study and other studies that have been found to affect the likelihood of SSI were entered into risk adjustment models. The primary outcome measure was the 30-day SSI incidence (defined by US Centers for Disease Control and Prevention criteria for superficial and deep incisional SSI). Relationships with explanatory variables were examined using Bayesian multilevel logistic regression models. This trial is registered with ClinicalTrials.gov, number NCT02662231. Findings: Between Jan 4, 2016, and July 31, 2016, 13 265 records were submitted for analysis. 12 539 patients from 343 hospitals in 66 countries were included. 7339 (58·5%) patient were from high-HDI countries (193 hospitals in 30 countries), 3918 (31·2%) patients were from middle-HDI countries (82 hospitals in 18 countries), and 1282 (10·2%) patients were from low-HDI countries (68 hospitals in 18 countries). In total, 1538 (12·3%) patients had SSI within 30 days of surgery. The incidence of SSI varied between countries with high (691 [9·4%] of 7339 patients), middle (549 [14·0%] of 3918 patients), and low (298 [23·2%] of 1282) HDI (p < 0·001). The highest SSI incidence in each HDI group was after dirty surgery (102 [17·8%] of 574 patients in high-HDI countries; 74 [31·4%] of 236 patients in middle-HDI countries; 72 [39·8%] of 181 patients in low-HDI countries). Following risk factor adjustment, patients in low-HDI countries were at greatest risk of SSI (adjusted odds ratio 1·60, 95% credible interval 1·05–2·37; p=0·030). 132 (21·6%) of 610 patients with an SSI and a microbiology culture result had an infection that was resistant to the prophylactic antibiotic used. Resistant infections were detected in 49 (16·6%) of 295 patients in high-HDI countries, in 37 (19·8%) of 187 patients in middle-HDI countries, and in 46 (35·9%) of 128 patients in low-HDI countries (p < 0·001). Interpretation: Countries with a low HDI carry a disproportionately greater burden of SSI than countries with a middle or high HDI and might have higher rates of antibiotic resistance. In view of WHO recommendations on SSI prevention that highlight the absence of high-quality interventional research, urgent, pragmatic, randomised trials based in LMICs are needed to assess measures aiming to reduce this preventable complication

    Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions

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    We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
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